PERITONEAL PERMEABILITY

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Altered permeability of the peritoneal membrane after using hypertonic peritoneal dialysis fluid.

Previous work has shown that use of hypertonic peritoneal dialysis fluid (7% glucose) results in ultrafiltration and enhanced urea transfer across the peritoneal membrane. Simultaneous creatinine studies showed a similar enhancement with hypertonic fluid which persisted in lesser degree during subsequent isotonic exchanges. The mechanism of solvent drag has been shown to contribute significantl...

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Intraperitoneal heparin reduces peritoneal permeability and increases ultrafiltration in peritoneal dialysis patients.

BACKGROUND Patients on long-term treatment with peritoneal dialysis (PD) suffer from increasing peritoneal permeability and loss of ultrafiltration as a result of persistent inflammation, which may be triggered by bioincompatible dialysis fluids. Heparins have anti-inflammatory and anticoagulant properties. We have examined the effect of intraperitoneal (IP) low-molecular weight heparin (tinzap...

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New insights in the molecular mechanisms regulating peritoneal permeability.

Peritoneal dialysis (PD) is used in approximately 15% of dialysis patients worldwide. With the reduction of acute peritonitis, the major problem associated with PD is now the high incidence of ultrafiltration (UF) failure, which can affect up to 50% of PD patients treated for more than 6 years w1x. Cross-sectional and longitudinal studies have shown that peritoneal permeability for small solute...

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Increased peritoneal permeability at peritoneal dialysis initiation is a potential cardiovascular risk in patients using biocompatible peritoneal dialysis solution

BACKGROUND Cardiovascular disease is a frequent cause of death in peritoneal dialysis patients. Biocompatible peritoneal dialysis solutions with neutral pH have been anticipated to reduce cardiovascular disease more than conventional peritoneal dialysis solutions with low pH, but it remains unclear which factors at peritoneal dialysis initiation increase cardiovascular risk in patients using bi...

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ژورنال

عنوان ژورنال: The Japanese Journal of Urology

سال: 1968

ISSN: 0021-5287,1884-7110

DOI: 10.5980/jpnjurol1928.59.3_222